Protein

Protein accession
2WEp8 [EnVhog]
Representative
3uisM
Source
EnVhog (cluster: phalp2_33955)
Protein name
2WEp8
Lysin probability
99%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MNKPERALFIRAACSAQSKNIKEDPIMPDRINTPFTNEHFTDWCLKMAEKKSPYWYGCCVYKASASKLASKTAQYPDHYGSGRTARYKQDIANKQVVADCVGGCKGYAWTNGGQGVLEAIGTDNTFTNKYASNSCPDQSANGMFSYCKKKGMDWGVIGTLPEIVGLALFTDGHIGYYVGGGYAVEWRGFNYGCVKTRVKDRTWKHWAKLPFIDYGEGVAAQPAIDAPTAEYTLGSRLLKKGMTGSDVKTLQELLNQLHIVTPALEVDGDFGNKTDAAVRAFQKKLRLKQDGLYGEETHKALMGAVADDDEGKKAQEPAVEEPEQPTVDQPDDSGTGPMVTIVCGDGTVNIRMGNSTDFARITAVKNGARFPYIATAANGWHAVLLESQIGWVSGKYSKVS
Physico‐chemical
properties
protein length:400 AA
molecular weight:43654,9 Da
isoelectric point:7,92
hydropathy:-0,44
Representative Protein Details
Accession
3uisM
Protein name
3uisM
Sequence length
373 AA
Molecular weight
40641,18210 Da
Isoelectric point
5,59355
Sequence
MDMEARKLVPLTNEHFAAFLENMLGAPYWYGTCMYKCTEALRARKARQYPSHYSEKRTAQYKRDIEEKKVCADCIGAAKGYAWTDGGQGVIEAIGTDAAIANRYGSNKCPDKGANGMFAYAKSKGMAWGTIDTIPEIVGLAVTTAGHVGYYIGGGYVIEFKGFAYGSVKTELKKGKWTHWYMLPFLDYGTADVTPSEQPDAGENQDATYTLGSRLLKKGSQGEDVRELQRILLELGYALGSYGEGGDGVDGKFGAATEKAVRAFQRNQQIAVDGKYGSVTHAALMGALADQDAMNTDDAQDENETPEGKTLRITADGVNVRTGPDKAFKIITRVNRGERFEYVATAEKQGWYAALIGGKVGWVCGEYAEVEEA
Other Proteins in cluster: phalp2_33955
Total (incl. this protein): 135 Avg length: 347,3 Avg pI: 7,73
Protein ID Length (AA) pI
3uisM 373 5,59355
10E61 362 7,96012
13ELM 367 8,29980
14Wus 352 8,54111
15JS4 374 8,09628
1G1bU 307 4,71686
1GLw3 364 5,49044
1Nygy 328 5,51875
1gA9g 351 7,10575
1gCbd 284 9,17877
1gD45 355 9,23711
1gGxn 347 6,42783
1kdFN 361 5,30179
1m5k7 364 5,64811
1nXn2 373 7,11746
1no8J 381 8,94236
1no9L 359 5,34942
1qC2H 280 8,90400
21mSf 334 8,79144
23yeL 302 5,25212
24sho 301 5,19244
2L7PK 291 8,13219
2Pb7g 373 8,29768
2WF1c 361 8,87744
2WF4k 367 8,34010
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_34532
4UelR
 2 39,8% 369 6.854E-116
2 phalp2_31501
3TJjZ
 324 38,9% 277 1.505E-82
3 phalp2_23391
5URxG
 99 37,3% 241 2.177E-57
4 phalp2_32958
3ZDZv
 229 33,8% 272 5.434E-48
5 phalp2_20477
3TDR4
 13 31,5% 295 4.046E-46
6 phalp2_34071
8r4Zl
 11 36,7% 245 1.018E-45
7 phalp2_29727
1mb2p
 5 29,7% 249 1.177E-40
8 phalp2_9688
23BCv
 75 31,9% 282 1.512E-36
9 phalp2_18241
4Udjz
 1 24,0% 353 2.050E-36
10 phalp2_21023
7YTt
 3 27,9% 301 1.955E-34

Domains

Domains
Unannotated
PG_1
SH3_3
Representative sequence (used for alignment): 3uisM (373 AA)
Member sequence: 2WEp8 (400 AA)
1 373 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3uisM) rather than this protein.
PDB ID
3uisM
Method AlphaFoldv2
Resolution 85.80
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50