Protein

Protein accession
2lEc3 [EnVhog]
Representative
6q8ry
Source
EnVhog (cluster: phalp2_38065)
Protein name
2lEc3
Lysin probability
99%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MALKGNTDEARIWNFCIAQGLTEAGAAGLMGNLYAESALNPKNLQNSYEKKLGHTNDSYTAAVDNGTYGNFVRDCAGYGLAQWTYWSRKEALLAFARSEGASIGDLEMQLKFCFKELSTGYKTVLNTLKTATTVRAASDSVLLKFERPADMSAAAQERRASYGQKYFDKYAGAGDTEKKEENKVGKMKSAAFVEKLIDIAKNYKTLYVMGCFGAPMNAENKQRYTTNHKYNKDATRTAMIKAASADTFGFDCVCLIKGVLWGWSGDASKRYGGAGYAVNGVPDIGADQMIKVCSGVTTDFSKIEVGEALWCEGHIGVYIGDGLGVECTPRWDNDVQITAVANIGSKTGYNARTWKKHGKLPYIDYVGAATDTTVPAEKPSTTAQGFKIGDIVDFKGNTHYTNANASSGKPCRSGKAKITSIYSKGKHKYHVVAVKGGGSNVYGWVDAADLDGAEEIKAGSKVRVKEGAKTYTGGRLASFVYKRDHIVKEINGKRAVIAYGGVVVAAVNTDDLTLV
Physico‐chemical
properties
protein length:515 AA
molecular weight:55571,2 Da
isoelectric point:9,00
hydropathy:-0,35
Representative Protein Details
Accession
6q8ry
Protein name
6q8ry
Sequence length
506 AA
Molecular weight
54484,58680 Da
Isoelectric point
8,51855
Sequence
MALVGTTTEEKIWNYLKGKGLSDCGIAGMMGNLYAESGLKPTNLQNSFEKKLGFTDDTYTTAVDNGDYTNFVKDSAGYGLAQWTYWSRKQNLLNFARAKGASIGNLEMQLDFLYKELSEGYKAVLSILKSAKSVREASDAVLLKFERPADQSTSVQVKRAGYGQKYYEKYAGGNKNMAKKVFLGVGHGGSDPGAVKYIKEADVNLQMALACRDYLQANGVEVKMSRTVDENDPLTDEIKECNSFNPDLAVDIHNNAGGGDGFEAYYYHGGGTSKTLAANIEAEVLKIGQNSRGLKTKLNSAGTDYYGFIRCINAPSVICEGVFVDNKADASQADELSEQKAFGIAYAKGILKTLGVADSKPSTPAASTPSASAGSDSVKTFPAVPFQVQVLVSDLNYRSEPSMDGKVKGQTGKGTFTITEVKDGWGKLKSGAGWIWLENPSYCTVKGTVASSQATQTQASSKKSVEEIAKEVIQGKWGNGGDRKKRLEAAGYSYSQVQAAVNRLCK
Other Proteins in cluster: phalp2_38065
Total (incl. this protein): 127 Avg length: 492,7 Avg pI: 8,38
Protein ID Length (AA) pI
6q8ry 506 8,51855
135Sb 443 6,20161
137je 541 9,25529
13BxT 504 9,06111
13atO 403 5,76520
13bDj 428 9,10811
13u0A 497 7,05977
1jF1c 477 5,43991
1ktUd 505 9,02211
1n0ZV 491 7,70705
21Mp4 514 9,44863
2nWID 538 9,42968
2pfFt 516 9,41356
3Pytv 486 7,50874
3Q2EW 473 8,74438
3dX1t 419 6,22241
3fJqN 514 9,39615
3kwV3 474 5,35852
3lOpV 515 5,95646
3m1eF 511 8,91786
3nxEz 504 9,48892
3o9OC 475 8,98536
3pjgw 502 9,09186
3ppG7 520 9,37701
3qmEn 505 9,12855
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25258
7XZmQ
 197 40,7% 422 1.429E-104
2 phalp2_39893
1dRNc
 8 31,3% 549 5.307E-102
3 phalp2_4467
3dQGl
 291 44,7% 351 4.690E-101
4 phalp2_2557
6ucjN
 5 39,8% 319 2.026E-78
5 phalp2_30431
7DEWH
 4 28,9% 459 5.118E-78
6 phalp2_11795
85Kwh
 1 28,7% 466 1.417E-49
7 phalp2_16871
1Ny9d
 1 32,9% 361 1.607E-45
8 phalp2_29540
3v8t1
 106 20,4% 343 7.557E-37
9 phalp2_8060
5LPSD
 13 30,7% 338 4.364E-24
10 phalp2_3787
5STbs
 32 27,5% 348 7.413E-22

Domains

Domains
Phage_lys2
Ami3
Unannotated
CW_7
Representative sequence (used for alignment): 6q8ry (506 AA)
Member sequence: 2lEc3 (515 AA)
1 506 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF08230, PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6q8ry) rather than this protein.
PDB ID
6q8ry
Method AlphaFoldv2
Resolution 89.45
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50