Protein

Protein accession
4ewyA [EnVhog]
Representative
4MkR6
Source
EnVhog (cluster: phalp2_10966)
Protein name
4ewyA
Lysin probability
85%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MICEFEGYHTALPDGGCTAYLCPAGVVTIGFGCTEGVKMGDVWTREQAEDALRRELATHEAAVNRLVTVDITRGQRDALISFSYNLGSGALAKSALLKKLNAGDNAGACAEFAKWNKAGGKVLRGLTIRRAKEAAMFASRDEPAPMPQKVDVPKEPMTPLQIATVVGGGATAVNQAVPVLPSISKSGGDAIDMMAGVKQIGGALQEFATWASANPKLALPGFLLVILPLLLPYVQAYLPTKAK
Physico‐chemical
properties
protein length:243 AA
molecular weight:25525,4 Da
isoelectric point:8,56
hydropathy:0,11
Representative Protein Details
Accession
4MkR6
Protein name
4MkR6
Sequence length
245 AA
Molecular weight
26701,77260 Da
Isoelectric point
10,12078
Sequence
MTPLTPTTTPQEAIDLIKKMEGLRLRAYRDIGGVWTIGYGHTSAGGPPEVGPGLTISRERAEQILLADVARVASEIQPHIERKVTRHQFAALLCFAYNVGAGNFRRSSVLKAVNDGDFAAVPRRLALWNKVGGRSVPGLIRRRAEEAALFACAEHPEEARDKMLRGDIPPGPLSKPRGKPPTRSTINVAAILSALAGLLSTVTGMFRDIGSLPLGHWTLPVMLVILVATMWIIRERRHKSELEGV
Other Proteins in cluster: phalp2_10966
Total (incl. this protein): 70 Avg length: 205,2 Avg pI: 8,89
Protein ID Length (AA) pI
4MkR6 245 10,12078
104OD 221 4,18457
173py 212 9,43052
1JzMV 230 9,64687
1N9lu 193 9,06504
1XdjU 236 9,24691
1bJUf 169 8,97524
1plUM 178 10,11575
2UKOv 169 8,97505
2VMtx 169 8,77706
2kUKy 152 9,58679
340el 243 9,57802
3MKXy 169 8,97505
3MMvM 169 9,29855
3OBNi 169 9,11469
3Ob3v 169 9,27296
3OwiX 169 9,13428
4EERf 169 9,06034
4EJ1d 169 9,15504
4MJwi 243 5,90957
4SQU3 205 9,73042
4eGJE 251 7,58939
4eUBt 209 9,54611
4f3t2 236 8,82754
4fEiw 243 9,76453
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2498
5GMvl
 297 35,9% 239 2.970E-62
2 phalp2_40579
4SZ2W
 11 36,3% 209 1.761E-60
3 phalp2_6830
8n5Jv
 121 43,3% 159 3.299E-60
4 phalp2_29738
1pBjt
 830 42,5% 200 6.181E-60
5 phalp2_2176
3Yhf4
 930 43,5% 163 1.757E-57
6 phalp2_26378
1q5mp
 207 33,3% 234 1.155E-56
7 phalp2_30676
6Q25R
 25 45,5% 156 4.020E-53
8 phalp2_15045
7iQxx
 18 44,9% 149 1.409E-52
9 phalp2_17663
6R9yG
 6 40,0% 150 3.971E-50
10 phalp2_8851
2IyxA
 73 41,8% 160 1.390E-49

Domains

Domains
GH24
Disordered region
Representative sequence (used for alignment): 4MkR6 (245 AA)
Member sequence: 4ewyA (243 AA)
1 245 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4MkR6) rather than this protein.
PDB ID
4MkR6
Method AlphaFoldv2
Resolution 78.74
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50