Protein

Protein accession
5M9Cy [EnVhog]
Representative
3pnB5
Source
EnVhog (cluster: phalp2_3379)
Protein name
5M9Cy
Lysin probability
99%
PhaLP type
endolysin
Probability: 94% (predicted by ML model)
Protein sequence
MTKKEFVSLLGEQARADMAKTGILASLTTAQGILESGYGTRELAVNANNIFGMKAELSGNNWPSDWGGQTYTKETNEQKPNGEVYTITAAFRKYESMAESIKDHSDYLAGAKKGNDLRYAGLVGERDYKKAIQIVKAGGYATDNNYVSKICSIVEKWNLTQYDTQEAGQNMNIKIIDATMKKSPCLTGGRTIKPIGPYLHSIGCPCEKAMNIINNENRADAGAGVHAVIQHTGEVYVGLPIDPEKKTAVRNWHGGSGPKGSCNNTHIGVEMTEPATIKYTGGASWIELSDGSNTKAVVLKNYRNAVEYFAYLCQKFGWNPEKDGVILSHSEGHARGYATNHADVEHIWKKYGLTMDQFRKDVKAAMAGGAISVSGSPTVTDTGVQDVKALSGTVTVIYTGSDGLNVRTTPSFASGNVKKVVNNGEAFTVTGISKDEKWYQINDGGAKAYITAVPDYVSFKATPEQKASTAGTGYFRVRKDWKDAASQIGAFKDRENAVELAKQNAGYYVFDNDGNRIYPEAPAAPVAAEYKVNVTTSDLRIRKGPGTTFDYWKKDGKPVYTGKGAFTIVEEAEGPGASKWGLLKAYAAGRNGWVSLDYAKKA
Physico‐chemical
properties
protein length:602 AA
molecular weight:65209,4 Da
isoelectric point:8,78
hydropathy:-0,49
Representative Protein Details
Accession
3pnB5
Protein name
3pnB5
Sequence length
502 AA
Molecular weight
53916,03880 Da
Isoelectric point
7,55802
Sequence
MEKQTFIQTVGEAAHKDMEKSGVLASLTIAQAILESGWGTSELAQNANALFGIKADSRWSGKAYSKETQECYDGVNYTTVTALFRAYGSWDESIADHSTFLLTGSRYAAVIGEKDYKTACKAIKAAGYATAPDYAEKLISLIESYGLTAYDGDVQKEEPTLKIIESILTKNPCYTGGRKLAAVKGLMLHSVGCPQPSAQVFVKNWNSPSHDSSCVHGFIDGNTGDVYQCLPWDWRGWHGASGPKGSCNNTHIGVEMCEPSTIKYTGGASWVETGDGTNTKATVMRTYKSAVELFAYLCKKFGLNPLGDGVIISHSEGHKRGIASNHGDVEHIWNKFGLTMDQFRRDVKETMDKESGGEKPQQPENKPAGGSTLYYVQAGAFSKKENAEAHAKALKAAGFDTTLKTADGLYKVQTGAYSVKANADAQVKALKAAGFDAFVTTNGGSAAPAPSYIEYTVKKGDSLWAIAAKLLGDGRRYTEIKVLSGLTGDTIYAGNVLKVPAK
Other Proteins in cluster: phalp2_3379
Total (incl. this protein): 146 Avg length: 584,1 Avg pI: 8,79
Protein ID Length (AA) pI
3pnB5 502 7,55802
13GuK 602 9,10134
17Wi 498 6,14727
1lAr 518 8,60113
1lZsC 602 8,96209
1ndAX 602 8,96209
2xDm 602 8,95764
3kEyQ 602 8,67811
3l0Mr 602 8,77951
3llYs 602 9,05222
3p2Ty 602 8,77539
3pxjf 602 9,01379
3rQdC 602 8,69777
3rc5e 602 8,84837
3rdEi 764 8,49321
3tVfH 602 8,96209
3tewQ 602 9,00915
3uUQu 344 9,43187
3wpxG 602 8,77146
4UFWS 490 8,56277
5C0Ar 602 8,88840
5LEv7 602 8,88421
5LJb0 602 8,84405
5Lgj1 602 8,85262
5M4W0 602 8,83160
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28222
obeB
 2 51,2% 365 1.462E-124
2 phalp2_40045
3tNNt
 34 38,6% 396 2.473E-102
3 phalp2_17183
3bJIf
 458 40,0% 370 2.321E-94
4 phalp2_20828
6lIKR
 83 26,4% 488 6.367E-58
5 phalp2_28439
1KvxT
 4 33,0% 309 4.346E-54
6 phalp2_21762
3TRfz
 37 24,6% 410 4.183E-36
7 phalp2_22435
KIGS
 311 24,0% 357 1.931E-34
8 phalp2_11372
7BXB0
 3 28,9% 325 1.638E-31
9 phalp2_29817
23g92
 1 25,2% 492 3.187E-27
10 phalp2_38692
MSLD
 8 24,6% 349 7.594E-26

Domains

Domains
GLUCO
Ami2
SPOR
LysM
Representative sequence (used for alignment): 3pnB5 (502 AA)
Member sequence: 5M9Cy (602 AA)
1 502 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01510, PF01832, PF05036

Taxonomy

  Name Taxonomy ID Lineage
Phage Unknown from Metagenome
[NCBI] 		UNKNOWN_ENVHOG No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)

No CDS data available.

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3pnB5) rather than this protein.
PDB ID
3pnB5
Method AlphaFoldv2
Resolution 88.15
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50