Protein

Protein accession
A0A2H4PFT0 [UniProt]
Representative
8MIMB
Source
UniProt (cluster: phalp2_11453)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAEKLLPYDRSIVPQETGYWCGPAATQVVLNSRGIIKAESDLARQIGTTTRGTDYVGLIERVLDAIVPDARYTSVYIENDPPTSAQKETLWRNLVASINAGYGVVMNWVAPPSNKPRGVKGSVSPSYSGGTTYHYVAAMGYDDNPAARAVWIADSGFRPYGYWVSFDQCATLIPPKGYCYAAAPAAPAAPSTPAPAVDAVTLLAQAMSPTEVSRETLALYLPHFAEAMRAAEITTVRRAAAWCSQVGHESAGLRYMAEIQTDGPGWTEDRRRYRGRGPIQLTWSSNYREFGQWCAARGYVTDPELFVKLPELVEQPRWGFLAASWYWLHGGPKPGQINAYADAGDILAVSRCVNGWIEGTNPVGWPDRQDRWNRCLALGDQLLTLATTTPTDPLEELLMTNLRVPSMSIYATPGEPDVPIIDMIRALDAHGDHESYVERQALLGDTDAIARIVRTAAGKGKYGNAPGPVNQAKDALKQIEAVNPAALEQFLDNQKGSIA
Physico‐chemical
properties
protein length:499 AA
molecular weight:54391,7 Da
isoelectric point:5,45
hydropathy:-0,27
Representative Protein Details
Accession
8MIMB
Protein name
8MIMB
Sequence length
456 AA
Molecular weight
49180,98030 Da
Isoelectric point
5,67062
Sequence
MAEKLLPYDRSIVPQETGYWCGPAATQVVLNSRGIIKAESDLARQIGTTTRGTDYVGLIERVLDAIVPDARYTSVYIENDPPTAAQKETLWRNLVASINAGYGVVMNWVAPPSNKPRGVKGSVSPSYSGGTTYHYVAAMGYDDNPAARAVWIADSGFRPYGYWVSFDQCATLIPPKGYCYAAAAPAAPAAPSAPAPAAQLSTKDQHALTIMRKGQEMGITPRGIKIALAVALVESNITVYANPKVPESMVIPHEAVGNDGRSVGIFQQQVVWGNGAWWWGDAATCMDPASSAALFYDRLLKLDYNNTSRSPGSYAQSVQQSAYPTRYDERFAEAEQLYVRLISQVTPADPIEELLMSNLRVPSLSIYATPGEPDVPIIDMIRALDAHGDHESYVERQALLGDTDAIARIVRTAAGKGKYGNAPGPVNQAKDALKQIEAVNPAALKQFLDNQKGSVA
Other Proteins in cluster: phalp2_11453
Total (incl. this protein): 173 Avg length: 514,3 Avg pI: 5,58
Protein ID Length (AA) pI
8MIMB 456 5,67062
171Ur 453 6,51741
1I1dT 433 5,24524
7As3I 451 5,52597
7AsRx 451 5,66153
7Q1Iw 502 6,04815
7ZSXT 461 5,86353
7jyTJ 454 5,66698
7pZeQ 457 5,01021
7zQXg 453 5,66693
8Ilx6 502 5,69790
8Ilxa 454 5,93464
8MmwX 502 6,04610
A0A4Y6EWN4 456 5,67062
A0A345M6H3 207 5,89900
A0A249XU47 525 5,20460
A0A2H4PCY0 499 5,58048
A0A514DDJ1 546 4,98952
A0A482JFG7 516 6,89812
A0A2R4A258 521 5,53364
A0A6M3T401 517 5,44531
A0A3S9UNQ2 516 5,63169
A0A3G3M9P4 239 9,13532
A0A5Q2WGF8 239 9,34406
A0A7G8LIK8 249 9,19134
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9506
1175H
 95 54,2% 339 4.445E-119

Domains

Domains [InterPro]
PET_C39
Unannotated
Unannotated
Representative sequence (used for alignment): 8MIMB (456 AA)
Member sequence: A0A2H4PFT0 (499 AA)
1 456 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Andies
[NCBI] 		2047834 Charlievirus > Charlievirus Andies
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MG099936 [NCBI]
CDS location
range 22011 -> 23510
strand +
CDS
GTGGCTGAAAAGCTGCTGCCGTACGACCGCAGCATCGTCCCGCAGGAAACCGGCTACTGGTGCGGCCCCGCGGCGACGCAGGTAGTGCTGAACTCGCGCGGCATCATCAAGGCCGAATCCGACCTCGCCCGCCAGATCGGCACCACCACCCGCGGCACCGACTACGTCGGCCTCATCGAGCGGGTACTCGATGCGATCGTGCCCGACGCTCGCTACACCTCGGTATACATCGAGAACGACCCGCCGACCTCGGCGCAGAAAGAAACCCTGTGGCGCAACCTCGTTGCGTCGATCAACGCCGGGTACGGCGTCGTCATGAACTGGGTTGCGCCGCCGAGCAACAAGCCGCGCGGCGTCAAAGGCAGTGTGTCGCCGTCCTACTCGGGCGGCACCACCTACCACTACGTGGCGGCGATGGGTTACGACGACAACCCGGCCGCCCGCGCGGTGTGGATCGCCGACAGCGGATTCCGGCCCTACGGCTATTGGGTGAGTTTCGACCAGTGCGCCACCCTGATCCCACCGAAAGGCTACTGCTACGCCGCCGCGCCGGCCGCCCCCGCGGCACCCTCGACGCCCGCGCCGGCCGTCGACGCGGTCACGCTGCTGGCGCAAGCGATGAGTCCAACCGAGGTGTCGCGCGAGACGTTGGCGCTTTATCTGCCGCACTTCGCCGAGGCGATGCGCGCTGCCGAGATCACCACGGTGCGCCGCGCCGCGGCCTGGTGCAGCCAGGTCGGCCACGAGAGTGCCGGGTTGCGCTACATGGCCGAGATTCAAACCGATGGCCCCGGGTGGACCGAGGACCGTAGACGGTACCGAGGCCGCGGCCCGATCCAGCTCACCTGGTCGTCGAACTACCGCGAGTTCGGGCAATGGTGCGCCGCACGCGGTTACGTCACCGACCCCGAACTGTTCGTCAAACTGCCCGAGCTTGTCGAGCAGCCGAGGTGGGGATTCCTCGCCGCGTCGTGGTACTGGCTGCACGGCGGCCCGAAACCCGGCCAGATCAACGCCTACGCCGACGCCGGCGACATCCTCGCGGTGTCCCGCTGCGTCAACGGGTGGATCGAGGGCACGAACCCCGTCGGATGGCCCGACCGGCAGGACCGCTGGAACCGCTGTCTCGCCTTGGGCGACCAACTGCTCACGCTCGCAACCACCACCCCAACAGATCCCCTCGAGGAGTTGCTCATGACCAACCTGCGAGTCCCATCAATGTCGATCTACGCCACCCCGGGCGAGCCGGACGTGCCGATCATCGACATGATCCGCGCGCTCGACGCGCACGGCGACCACGAAAGCTACGTCGAGCGCCAGGCGCTGCTTGGCGACACCGACGCAATCGCACGCATCGTGCGCACCGCCGCCGGCAAGGGCAAGTACGGCAACGCACCCGGCCCGGTCAACCAGGCCAAAGACGCGCTCAAGCAGATCGAGGCCGTCAACCCGGCGGCCCTCGAACAGTTCCTCGACAACCAGAAAGGCAGCATTGCATGA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000ca13e6b_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8MIMB) rather than this protein.
PDB ID
8MIMB
Method AlphaFoldv2
Resolution 85.87
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50