Protein

Protein accession
A0A482GBA5 [UniProt]
Representative
8Mwp5
Source
UniProt (cluster: phalp2_29261)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MADTSKKYAQQQLGRFDPSYPQLATVMDNRDPTKSGKLKVWIQGSQSDKNSKESWIEASYMSPFAGKTPGIPSADAYGQYPKGYGFWAVPPDVGCTVVVIFAQARTFQAYWIGCVYDQRMNTMVPGMATEVSNYGGTDMPLPVTDYDRNTITTDMQDKYANVPIIAGLKKQNLLYDEEAGLANRSSTRQTTSTVYGMSSPRGNSFIIDDGYTEEELTAPTWDQDPDGYQDTQFNNPVNDTRVGSRKNEGVVIKTRSGAQLLLSEATGDVLLINRDGTARIKFTGEGDIDMHCDKNINIRAGQDINITAGRSYNIETGQDFNARVGANTKLDLIGALDAKVGGQVVVNSGADLRLVTAASLRMQSGSSTDITAGSNASISAATSANLIGSSSAIISGGGQTLTVNSGGNSGTAEFTAPNFRTPSAGLNEHIHDIAAWVNAENHGSYVEPPRQGGGSGSSESPVQPQPANDVSPELPVAQDTEAVQFVNYTSETEQVQSQDLMTSDPGMTGYSITYEGLHMLMPCSGTIRQYGYWGKGVPTQSGGKADRSGWEIQCKGDVVAPDGGVVVITNGALLIQHKSGYKSIFYNIQSDLLNKDVVQKGQVVGKANGVIQFEIRVTSANVLGFSGSVDPGLFYASQTGTGSDAANKTLIGGQATNQSAPKAVVQPSVDSDELVVTTKIKTIGTGYSQRGSRHVPRRRRTQRSGASTTPVEQPTYNIGNVDKTAIDWKVVPGDAQFISELKEYEGTLQYQQAKGYYRNGKFWRYLDSRGYPTIGYGHLIISGENFSDGITEQQANDMLVRDSSKAIYDAKSIYASYNMKTPYLAQQVLCQMVFQMGKGGVLKFKTMLSELAKGNYKQAAAQIRNSAWYRQTTRRAELMARRLEACQ
Physico‐chemical
properties
protein length:887 AA
molecular weight:95901,0 Da
isoelectric point:6,04
hydropathy:-0,47
Representative Protein Details
Accession
8Mwp5
Protein name
8Mwp5
Sequence length
893 AA
Molecular weight
96227,73990 Da
Isoelectric point
5,65920
Sequence
MGDNSTSKSMEFSKNQNARFNPQFVQLATVMDNRDPTKTGKLKVWVQNSQSDKDSKGSWLTASYLSPFAGRTPGTPGAESYQQFPKGYGFWAVPPDVGVTVAIFFANGNIHECWWFACGYDDRMNTMVPGAASQNMPNSGYDMPVPITDYDRNTIQTQLDQKYVNVPLVEGLKKQNLLYDAQKGVPNRSSTRQTISTTYGMASPRGNTFVMDDGYTDAELTAPNWDDDQDSYQNTQFNNPVNDTAVGTRKNEGIILRTRSGAQFLLSESDGNVFLINRDGTARFEMTVDGQILVHATKSITFRTEEDFNFTASRDINFEAGRNLNMSIQGDTKLNLVGKLDAIVNGQVVINAGADLRLVAGASIRVQSGSSTNITSGSNTAITASSTVDIKGSAVNIGGGGNNLTIKGDSTASTAPMGAPDFKTPSVGLSDHIHLHQSFVDASNHSDQMAPPVQGGGNSSADAPATAEPANDVAPEAPQQQAQETVQHVNSTSEVGQVLSQDLVVSDGGEDNTTVSYTTTYEGLQMFMPCTGTIREFGYWGKGVPTQSGSTTNRNGWIIQAKGDVVAPDGGLVTKISTGGLIITHPTGYKSVFYDINITVNNKDTVTKGQKIGTANGVFDFEIRLQSANIYGFSGTVDPGLFYSTVTGKGASAANKSLIAGKPSNLNPAPVTGYSENSSELVVITTVNSIGSVYSQRGSRHVPRRTSTTKRNTNSTARAPAEDLSSLDKTSIDWKVTASDGKLIEEVKEFEGTIQYQTAIGYFRGGRFWIYKDSLGYPTIGYGHLITANDNFPGGIDEPTADALLQKDLVRTVRDAQSIYAQYNMKTPYIVQIVLTEMVFQMGKGKVLKFKNTLAALASGDYKGAAAGIRNSAWYSQTPRRAEVMARRVEACE
Other Proteins in cluster: phalp2_29261
Total (incl. this protein): 67 Avg length: 616,4 Avg pI: 7,09
Protein ID Length (AA) pI
8Mwp5 893 5,65920
1dbUN 899 5,52943
1gMqY 897 5,55979
37Uyb 874 5,18749
3OAo6 676 5,45128
3OBjV 880 5,75537
3OpFL 891 5,96908
4Z5pf 899 5,46799
5hYUZ 891 5,92014
5ipz4 892 5,96908
71eSH 889 5,81016
7PFZq 887 6,04133
7PdEw 886 5,48555
885Om 887 6,31734
8J37d 894 5,58866
8J37f 887 6,04133
8J37j 894 6,02820
8LjeG 893 5,97954
CpyP 895 5,49363
A0A097EYH3 162 9,30081
H6X3N5 886 5,48555
K4F6U4 162 9,12758
K4FB41 894 5,58866
A0A097EYI1 887 6,04133
A0A1L2CUV5 894 6,02820
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9037
5ghTb
 15 24,8% 701 2.253E-43
2 phalp2_22943
3cStN
 49 22,5% 757 1.623E-21

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vB_EcoM_G17
[NCBI] 		2502408 Asteriusvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK327931 [NCBI]
CDS location
range 184713 -> 187376
strand +
CDS
ATGGCAGATACAAGTAAAAAGTATGCACAACAGCAGTTGGGTCGTTTTGACCCATCTTATCCGCAGTTAGCAACTGTTATGGATAACAGAGATCCAACTAAATCAGGAAAACTGAAAGTTTGGATACAAGGTTCTCAAAGTGATAAAAACTCAAAAGAATCATGGATAGAAGCATCTTACATGTCTCCTTTTGCTGGTAAAACACCAGGTATTCCAAGTGCTGATGCATATGGTCAATATCCAAAAGGATACGGTTTTTGGGCAGTACCACCAGACGTAGGGTGTACAGTTGTTGTAATTTTTGCACAAGCCCGTACATTCCAAGCATATTGGATTGGTTGTGTATATGACCAGCGTATGAATACTATGGTTCCGGGTATGGCAACTGAAGTAAGTAATTATGGTGGAACTGATATGCCACTTCCTGTTACTGACTATGATCGTAACACTATCACTACCGATATGCAAGACAAATATGCTAACGTTCCAATCATCGCAGGTCTTAAAAAGCAAAACCTTTTATATGACGAAGAAGCTGGGTTGGCGAATCGTAGTAGTACTCGACAAACCACAAGTACTGTATATGGAATGTCATCACCACGTGGAAATAGTTTCATTATTGATGATGGATATACTGAAGAGGAATTAACTGCACCCACATGGGATCAAGACCCAGATGGATATCAAGATACGCAATTTAATAACCCAGTAAACGATACCCGTGTTGGTTCTCGTAAAAATGAAGGTGTTGTAATAAAAACACGTAGTGGTGCACAACTTCTTTTATCAGAAGCAACTGGTGATGTTCTTTTAATTAACCGTGACGGTACTGCACGTATTAAATTCACTGGTGAAGGTGATATTGACATGCATTGTGACAAGAATATCAATATTCGTGCAGGACAAGATATTAATATTACGGCTGGACGTTCATACAACATTGAAACCGGACAAGATTTCAATGCACGCGTTGGTGCAAATACTAAATTAGATCTAATTGGTGCTCTTGATGCAAAAGTTGGTGGACAAGTGGTGGTTAATTCAGGTGCTGACCTTCGTTTAGTTACGGCTGCATCATTACGTATGCAAAGTGGTAGCAGTACTGATATTACGGCTGGTTCAAATGCTTCTATTTCTGCCGCAACATCTGCAAACCTAATTGGATCATCATCAGCAATTATTAGTGGTGGTGGTCAAACATTAACAGTTAATAGTGGTGGTAATAGCGGTACTGCTGAATTTACTGCACCAAACTTTAGAACACCATCTGCTGGTCTTAATGAACACATTCATGATATCGCTGCATGGGTTAACGCTGAAAATCATGGTAGTTATGTTGAACCACCAAGACAAGGTGGTGGAAGTGGTTCTAGTGAATCACCAGTACAACCACAACCAGCAAATGATGTATCACCAGAATTACCCGTAGCACAAGACACTGAAGCTGTTCAGTTTGTTAACTATACATCAGAAACTGAACAAGTTCAATCACAAGATTTGATGACATCTGATCCTGGGATGACTGGATATAGTATTACATATGAAGGTTTACATATGTTAATGCCATGTAGCGGTACTATTCGACAATATGGTTACTGGGGGAAAGGTGTTCCAACACAAAGTGGAGGAAAGGCAGACCGTTCAGGTTGGGAAATACAATGTAAAGGTGATGTAGTTGCACCAGATGGTGGTGTGGTAGTAATTACTAATGGTGCTCTTTTAATACAACATAAGTCTGGATATAAATCTATTTTTTATAATATTCAATCTGATTTATTAAACAAAGATGTTGTTCAAAAAGGTCAAGTTGTTGGAAAAGCAAATGGTGTCATACAGTTTGAAATTCGTGTTACATCAGCAAATGTTCTTGGATTCAGTGGTTCTGTTGACCCAGGATTATTTTATGCTTCACAAACAGGAACAGGGTCTGATGCGGCGAATAAAACATTAATTGGTGGTCAAGCAACTAATCAATCTGCTCCAAAAGCAGTTGTACAACCTTCAGTTGATAGTGATGAATTGGTAGTTACAACAAAAATCAAAACGATAGGTACTGGATATTCTCAACGTGGTTCTCGTCATGTGCCTCGTAGGAGAAGAACACAGAGAAGTGGAGCTTCAACAACTCCGGTGGAGCAACCTACCTATAATATTGGAAATGTTGATAAAACTGCAATCGATTGGAAAGTTGTTCCAGGTGATGCACAATTTATTTCTGAATTAAAAGAATATGAAGGTACATTACAATACCAACAAGCAAAAGGATATTATCGTAATGGTAAATTCTGGCGTTATTTGGATAGTCGTGGGTATCCAACTATTGGTTATGGTCACTTGATTATTAGTGGTGAAAACTTTTCAGATGGAATAACTGAACAGCAAGCCAACGATATGTTAGTTCGTGATAGTAGTAAAGCTATATATGATGCTAAATCAATTTATGCTTCATATAACATGAAAACACCTTATTTGGCTCAACAAGTACTATGCCAAATGGTATTCCAGATGGGTAAAGGTGGGGTACTTAAATTTAAAACTATGTTGTCTGAATTAGCTAAAGGTAATTATAAACAAGCTGCTGCTCAAATACGTAATTCAGCTTGGTATCGCCAAACTACTCGCCGTGCTGAGTTAATGGCTCGTCGTTTAGAGGCATGTCAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
upi0002ab5823_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (8Mwp5) rather than this protein.
PDB ID
8Mwp5
Method AlphaFoldv2
Resolution 75.15
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50