Protein

Protein accession
A0A0F6YQU5 [UniProt]
Representative
1Mw6C
Source
UniProt (cluster: phalp2_1467)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MVTRANVEATKAFIRARLGNPYVYGGALSENVRQGTDCSEVWQTVLEMVHGRWVQGRQSEGATTESYRYIDVGQVGPFGTIRVNHWRDIPADAAARIAFHHGPGGGANSHMWGELDGMRIESGGSKGLVTGDRAMAVESSYATAWAYLPGPIGGTGSLGVGSTGPAVIALQHKLNERGAGLDVDGEFGPLTASAVTRAQQELHVVGDPPGVAGEATLRALGLLGADGAIPAQPNVLAAEYLAEATGVSVQKAQQMLPTMRDGLKQADATNVNRIAMFYAQTGHESANFNATEEYASGAAYEGRADLGNNYPGDGVRFKGRTWIQITGRHNYGEFSKWAHWKGLVPSPSYFLDHPQELSDLKWAGIGAAWYWTVQRPDINALSDRRDLDTVTRRINGGLNGIDERRTRYNRALAMGDKLLTVFASNEPQDEWDALMADQTRYPSRAWYRSDDVPAHTPLDLLRNIDGMKWDERVTQAAFRGEVWAIEAIAKVAKGEGPEKSPAAIEESKNLVRQLKAALAAQIGASQ
Physico‐chemical
properties
protein length:526 AA
molecular weight:56924,9 Da
isoelectric point:5,90
hydropathy:-0,41
Representative Protein Details
Accession
1Mw6C
Protein name
1Mw6C
Sequence length
436 AA
Molecular weight
47373,67620 Da
Isoelectric point
6,52429
Sequence
MTVLRSNVEATKAFIRARVGNPYVYGGALSNNVRQGTDCSEVWQTVLEMVLGRWRQGRQSEGATTESYRYIPVGGVGPFGTIRVANWRDIPGNAVARLAFHHGPGGGANSHMWGDLDGMRIESAGSKGLVTGGNARAIEDGYAHAWCYLPGPIDGGGAVPVESTEDLQRRLNTEGAGLEVDGEYGPLTASALAAYDKRVPYARQVKAEGERRGITPRGIQIAFSVVFVESGWKMYANSKVPESLKLPHDAVGSDHDSVGLFQQRCPMWGPANVLMDPTKSAGLFYDRLAKLDYNNQSRPPGDYAADVQRPAAQYRGRYQERMGHAVALYNRITTTPEPSDDLEALLMSDELFASRSIYRTSDQKTMSARDAIFGADACAHMTWIEQKALAGDSWAIGLVADLATGKLPASKDPWAVDRARHIISIIQNAIAAQETK
Other Proteins in cluster: phalp2_1467
Total (incl. this protein): 71 Avg length: 492,0 Avg pI: 5,88
Protein ID Length (AA) pI
1Mw6C 436 6,52429
2LVy0 426 5,36216
7dyXr 454 6,56885
ugp5 433 5,00782
A0A7D5JQW9 526 5,94743
A0A5J6T2E0 525 5,71814
G8I7N0 526 5,93083
A0A1C9M1F8 526 5,81499
G1D3T6 472 5,93316
A0A2D1GDJ1 472 5,63254
A0A5J6T3K6 466 6,21622
Q854L4 473 5,57638
A0A385DV82 472 5,60196
A0A0K2CPS6 526 5,81687
A0A142F1U1 466 6,21622
A0A142K4R9 526 5,93083
A0A1D8EY32 526 5,81687
A0A1D9CAG5 526 5,81499
A0A1S6L2C0 465 6,21622
A0A2P1A0V6 526 5,93083
A0A2P1A2H9 526 5,81687
A0A2P1A2Y7 526 5,93083
A0A2S1PBB3 472 5,60196
A0A2Z5H0T0 465 6,21622
A0A2Z5H107 466 6,21622
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23524
75PiN
 82 41,3% 532 1.583E-146
2 phalp2_3134
870ZT
 3 32,8% 429 1.242E-42

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 1Mw6C (436 AA)
Member sequence: A0A0F6YQU5 (526 AA)
1 436 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Luchador
[NCBI] 		1647300 Luchadorvirus > Lucadorvirus luchador
Host Mycobacterium smegmatis str. MC2 155
[NCBI] 		246196 Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae > Mycobacterium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KR080193 [NCBI]
CDS location
range 4568 -> 6148
strand +
CDS
ATGGTTACCCGCGCAAACGTCGAGGCCACCAAGGCATTCATCCGAGCGCGGCTGGGCAACCCCTACGTCTACGGCGGCGCTCTCTCCGAGAACGTCCGACAGGGCACAGACTGCTCCGAGGTCTGGCAGACCGTCCTAGAGATGGTGCATGGCCGCTGGGTCCAGGGCCGTCAGTCAGAGGGCGCTACCACTGAGTCCTACCGCTACATCGATGTCGGCCAGGTCGGCCCGTTCGGGACGATCCGCGTCAACCACTGGCGGGACATCCCGGCCGACGCTGCCGCTCGCATCGCGTTCCACCACGGTCCCGGAGGCGGGGCCAACTCGCACATGTGGGGCGAGCTTGACGGCATGCGGATCGAGTCAGGCGGCTCGAAGGGTCTGGTGACGGGCGACCGCGCTATGGCGGTCGAGTCGAGCTACGCCACGGCGTGGGCCTACCTCCCCGGTCCTATCGGCGGCACAGGCTCTCTGGGCGTCGGTTCCACCGGCCCTGCGGTCATCGCCCTGCAGCACAAGCTCAACGAGCGCGGCGCGGGCCTCGATGTCGACGGCGAGTTCGGTCCTCTTACCGCCTCAGCGGTCACCAGAGCGCAGCAAGAGCTTCATGTAGTCGGTGACCCTCCGGGTGTCGCTGGCGAGGCCACACTGCGTGCTCTGGGCTTGCTAGGCGCAGACGGTGCCATCCCGGCTCAGCCCAACGTGCTGGCCGCGGAGTACCTCGCGGAAGCGACCGGCGTCAGTGTCCAGAAGGCACAGCAGATGCTCCCGACGATGCGTGACGGTCTCAAGCAGGCCGACGCGACCAACGTCAACCGAATCGCGATGTTCTACGCCCAGACGGGCCATGAGTCAGCGAACTTCAACGCCACCGAGGAATACGCCTCGGGTGCCGCGTACGAGGGCCGAGCAGATCTCGGCAACAACTACCCCGGCGACGGCGTGCGGTTCAAGGGCCGGACATGGATCCAGATCACGGGTCGACACAACTACGGCGAGTTCAGCAAGTGGGCGCACTGGAAGGGGCTGGTCCCCTCCCCCTCCTACTTCCTCGACCACCCGCAGGAGTTGTCCGACCTGAAGTGGGCAGGCATCGGTGCCGCCTGGTACTGGACCGTCCAGCGACCGGACATCAACGCGCTGAGCGACAGACGCGATCTCGACACGGTGACGCGCCGAATTAACGGCGGTCTCAACGGGATTGACGAACGACGCACTCGATACAACCGAGCACTGGCGATGGGCGACAAGCTCCTCACCGTGTTCGCATCCAACGAACCACAAGACGAATGGGACGCACTTATGGCAGACCAGACCAGATACCCCTCGCGGGCCTGGTACCGGAGCGACGACGTTCCGGCACACACACCGCTCGACCTCCTTCGCAACATCGACGGCATGAAGTGGGACGAACGCGTCACACAGGCCGCTTTCCGTGGCGAGGTGTGGGCGATCGAAGCCATCGCGAAGGTCGCGAAAGGCGAAGGCCCAGAGAAGAGCCCGGCAGCCATCGAGGAATCGAAGAACCTCGTACGTCAACTCAAAGCGGCGCTCGCCGCACAGATCGGAGCATCCCAGTGA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000624397b_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (1Mw6C) rather than this protein.
PDB ID
1Mw6C
Method AlphaFoldv2
Resolution 87.24
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50