Protein

Protein accession
A9XKX5 [UniProt]
Representative
7Z48s
Source
UniProt (cluster: phalp2_28564)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
TVEAGRDEMAVGSHAKGYNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYEGAVLRAHHEVAPKACPSFDLKRWWEKNELVTSDRG
Physico‐chemical
properties
protein length:96 AA
molecular weight:10511,8 Da
isoelectric point:6,83
hydropathy:-0,35
Representative Protein Details
Accession
7Z48s
Protein name
7Z48s
Sequence length
201 AA
Molecular weight
22305,02020 Da
Isoelectric point
6,65644
Sequence
MRDVNRIFIHHSATTVDQTVNVEVLDQWHRARGFSGIGYHYVILRDGTVEKGRPELKVGAHVKNHNTGSLGICLVGGLNAQKKAENNFTDSQFNALRKLLKSLIDKYGEVEVLGHKEVAQTECPPFDVQAWLADNLAKTDAPSVKMSVEITPQIETQLKGIENGLANIRTLWSSSWSSSLQLELGGLEDCTKNLRSLLKND
Other Proteins in cluster: phalp2_28564
Total (incl. this protein): 97 Avg length: 141,1 Avg pI: 7,93
Protein ID Length (AA) pI
7Z48s 201 6,65644
T1PTT1 151 9,03055
A0A2H4P6C3 151 8,82606
Q2WC97 117 7,84717
A0A088FBW1 151 8,45749
A0A1I9SE91 152 7,77819
Q9T132 151 9,03055
E1XU94 151 8,46878
A0A289YLY8 151 9,03055
Q6WY45 151 8,80820
B3FYI8 151 8,79176
A0A385IPD3 151 8,79176
A0A6B9RJP7 151 8,82606
A0A3Q9I5D4 152 8,82542
A0A2K9VJV1 151 8,82606
A0A0E3M152 151 8,80833
A0A0U2DV48 151 8,79176
A0A172JFY8 151 9,03055
A0A193GYQ9 151 9,03055
A0A1P8EDQ7 151 8,79176
A0A2I7QJ07 150 6,28840
A0A2I7QQD0 150 6,28840
A0A2I7QSV6 150 6,28840
A0A2I7QU52 139 8,58946
A0A2I7QUC7 150 6,28840
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24237
2YSsA
 71 47,5% 145 1.191E-65
2 phalp2_35819
4CbZx
 312 42,5% 160 1.479E-64
3 phalp2_3887
6RreM
 7260 52,5% 137 1.143E-55
4 phalp2_11894
2jrH4
 329 49,2% 142 2.145E-55
5 phalp2_36193
72BPm
 409 51,4% 134 4.084E-52
6 phalp2_28171
8yYQh
 287 48,3% 153 1.070E-45
7 phalp2_23766
13ajC
 287 44,2% 131 4.645E-44
8 phalp2_11611
1k5JO
 2203 36,5% 145 3.045E-37
9 phalp2_12261
71VXz
 7 39,0% 151 1.068E-36
10 phalp2_23565
7vNZv
 154 43,4% 138 1.999E-36

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 7Z48s (201 AA)
Member sequence: A9XKX5 (96 AA)
1 201 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage T7 (Bacteriophage T7)
[NCBI] 		10760 Autographiviridae > Teseptimavirus > Teseptimavirus T7
Host Escherichia coli
[NCBI] 		562 Proteobacteria > Gammaproteobacteria > Enterobacteriales > Enterobacteriaceae > Escherichia >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
EF517040 [NCBI]
CDS location
range 1 -> 292
strand +
CDS
TACTGTGGAGGCAGGACGAGATGAGATGGCTGTAGGCTCTCACGCTAAGGGTTACAACCACAACTCTATCGGCGTCTGCCTTGTTGGTGGTATCGACGATAAAGGTAAGTTCGACGCTAACTTTACGCCAGCCCAAATGCAATCCCTTCGCTCACTGCTTGTCACACTGCTGGCTAAGTACGAAGGCGCTGTGCTTCGCGCCCATCATGAGGTAGCGCCGAAGGCTTGCCCTTCGTTCGACCTTAAGCGTTGGTGGGAGAAGAACGAACTGGTCACTTCTGACCGTGGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A9XKX5
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
upi000162d854_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7Z48s) rather than this protein.
PDB ID
7Z48s
Method AlphaFoldv2
Resolution 89.68
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50