Protein

Protein accession
S5YQM1 [UniProt]
Representative
7cDMo
Source
UniProt (cluster: phalp2_7770)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPRVVYGLTHSSNGWPMLNSDECEWTKIPGTSVTLQIAKGQPLAILRAFAADFHAYVEPLRDADSACWTPTNSVPSSNHLSGTAMDLNWNTHPFQVPDAGFDAAKKARVKELLDFYEGMVFWGNDWSSPKDAMHFQLASLRNGGNFDTYGNPKTADFIARKIRADGYSTFRRGSAPASAAPILAAATGLSEARAAEILPAVRSGLRESECTNVNRIAMWLAQIGHESGSFQYTEEIAKNGRYAPYIGRTWIQITWDYNYRSFSQWAYAFGMVPTPDYFVVNYRELADLKWAGIGPAWYWTVARPDINELSDRRDLNTVTRRINGGTNGLADRQARYNRALAQGDALLQLLHEEDDFLSALTDAEQRELLDLARQQAKYKRKSRSPLHWPHEGEVDTIAGLSWSTDANVHIQLVEKLAVIYGDPVSIALLYAVSNSDDPTNNPELAKRILKRVKPEDITAAQVQIQKWLAAEQKFHAA
Physico‐chemical
properties
protein length:477 AA
molecular weight:53340,0 Da
isoelectric point:6,15
hydropathy:-0,41
Representative Protein Details
Accession
7cDMo
Protein name
7cDMo
Sequence length
319 AA
Molecular weight
34915,66170 Da
Isoelectric point
5,85546
Sequence
MVLRTENGWYQVPASSCEWTTIPGTNVTLQIQKGWPLTIMRAFAADFNAYVEPLRDPDSACWTPTNSVATSNHLSGTAMDLNWNSHPFQVLNAGFDAAKIATIRELLAFYEDTIFWGNDWTTPKDAMHFQMGYDTYNNSHTQDFINRKIRPDGYSTFRRGEAPSVDVAQVLSDAMGGRLSLDRYAQLLPAVTASLLACDCTNVNRIAMWCAQIGHESAGLYYTEEIASGAAYEGRADLGNTQPGDGVRFKGRSWIQITGRSNYTRLSAWAFSKGLILPQPTSSTTPPRSHPTSTPASAPLGTGWSPAPTSTPCPMPATS
Other Proteins in cluster: phalp2_7770
Total (incl. this protein): 152 Avg length: 446,3 Avg pI: 5,93
Protein ID Length (AA) pI
7cDMo 319 5,85546
7owdR 353 6,97297
A0A2Z5XVP6 317 5,28338
A0A3G8FU95 477 6,28374
A0A3G8FTV5 477 6,15250
A0A345MAV1 461 5,86314
A0A515MIU4 477 6,15250
A0A3G8FJG9 477 6,15250
A0A2U8UGP9 477 6,03519
A0A345MFL4 461 5,86314
A0A0F6YQE4 464 6,09959
A0A0P0M638 489 5,92708
A0A0F6YRS1 314 5,28554
G1FGA6 458 6,03377
A0A0M4RSF9 490 5,75645
A0A2P1JV09 477 6,15250
G8IB48 470 6,03439
A0A3G8FT87 477 6,15250
G3MDN4 489 6,15057
A0A097EVK7 477 6,15154
A0A076G858 317 5,52096
A0A7T1KSS8 481 4,88340
K0G1C0 477 6,15250
Q854X2 317 5,54876
G1D359 476 5,98790
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24932
8Jrom
 307 58,4% 325 4.137E-140

Domains

Domains [InterPro]
PET_M15
Unannotated
Disordered region
Representative sequence (used for alignment): 7cDMo (319 AA)
Member sequence: S5YQM1 (477 AA)
1 319 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13539

Taxonomy

  Name Taxonomy ID Lineage
Phage Mycobacterium phage Wheeler
[NCBI] 		1383054 Fromanvirus >
Host Mycobacterium smegmatis str. MC2 155
[NCBI] 		246196 Actinobacteria > Actinobacteria > Corynebacteriales > Mycobacteriaceae > Mycobacterium >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KF416340 [NCBI]
CDS location
range 4616 -> 6049
strand +
CDS
ATGCCGAGGGTCGTCTATGGGCTGACCCACTCGTCCAACGGGTGGCCGATGCTCAACTCCGATGAGTGCGAGTGGACGAAGATCCCCGGCACGAGCGTCACGCTGCAGATCGCCAAGGGCCAGCCTCTCGCGATCCTGCGCGCGTTCGCCGCTGACTTCCACGCGTACGTCGAGCCGCTGCGCGACGCGGACTCCGCGTGCTGGACGCCGACCAACTCGGTCCCGTCGTCCAACCACCTGAGCGGCACCGCGATGGACCTGAACTGGAACACCCACCCGTTCCAGGTCCCGGACGCAGGCTTCGACGCCGCGAAGAAAGCACGGGTCAAAGAGCTACTCGACTTCTACGAGGGCATGGTGTTCTGGGGCAACGACTGGTCGTCGCCCAAGGATGCGATGCACTTCCAGCTCGCCAGCCTCCGCAACGGTGGCAACTTCGATACCTACGGCAACCCGAAGACAGCCGACTTCATCGCGCGCAAGATCCGCGCTGACGGCTACTCGACTTTCCGGAGGGGTAGCGCCCCGGCGTCCGCAGCCCCCATCCTGGCGGCGGCCACCGGCCTGAGCGAAGCTCGCGCGGCGGAGATCCTGCCCGCGGTTCGCTCGGGCCTCCGGGAATCCGAATGCACGAACGTCAACCGCATCGCGATGTGGCTGGCTCAGATCGGACACGAGTCCGGGTCGTTCCAGTACACCGAGGAGATCGCCAAGAACGGGCGGTATGCGCCGTACATCGGCCGGACGTGGATTCAGATCACCTGGGACTACAACTACCGGTCGTTCTCGCAGTGGGCGTACGCGTTCGGGATGGTTCCGACTCCGGACTACTTCGTCGTGAACTACCGCGAGCTCGCTGATCTGAAGTGGGCGGGCATCGGCCCTGCCTGGTACTGGACGGTCGCCCGCCCGGACATCAACGAGCTGTCCGACCGCCGCGACCTGAACACGGTCACCCGCCGGATCAACGGCGGCACCAACGGCCTCGCGGATCGACAAGCCCGCTACAACCGCGCGCTCGCCCAGGGCGATGCGCTGCTGCAACTACTTCACGAAGAGGACGACTTCTTGTCTGCTCTAACCGACGCTGAACAGCGTGAGTTGCTGGACCTGGCTCGCCAGCAGGCCAAGTACAAGCGCAAGTCCCGCTCTCCGCTGCACTGGCCGCACGAGGGCGAGGTCGACACGATCGCCGGCTTGTCCTGGTCGACGGACGCGAACGTCCATATCCAGCTGGTCGAGAAGCTCGCTGTGATCTACGGCGACCCGGTCTCGATCGCGCTGCTGTACGCGGTGTCGAACTCCGACGATCCGACGAACAACCCCGAGCTGGCGAAGCGCATCTTGAAGCGCGTCAAGCCCGAGGACATCACCGCTGCTCAGGTCCAGATCCAGAAGTGGCTGGCTGCCGAGCAGAAGTTCCATGCCGCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000218e64e_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7cDMo) rather than this protein.
PDB ID
7cDMo
Method AlphaFoldv2
Resolution 85.95
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50