Protein

Protein accession
A0A1W6JQ85 [UniProt]
Representative
7kL3N
Source
UniProt (cluster: phalp2_27772)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKTYSEARARLRWYQGRYIDFDGWYGYQCADLAVDYIYWLLEIRMWGNAKDAINNDFKNMATVYENTPSFVPQIGDVAVFTKGIYKQYGHIGLVFNGGNTNQFLILEQNYDGNANTPAKLRWDNYYGCTHFIRPKYKSEGLMNKITNKVKPPAQKAVGKSASKITVGSKAPYNLKWSKGAYFNAKIDGLGATSATRYGDNRTNYRFDVGQAVYAPGTLIYVFEIIDGWCRIYWNNHNEWIWHERLIVKEVF
Physico‐chemical
properties
protein length:251 AA
molecular weight:29057,6 Da
isoelectric point:9,25
hydropathy:-0,48
Representative Protein Details
Accession
7kL3N
Protein name
7kL3N
Sequence length
163 AA
Molecular weight
18993,33920 Da
Isoelectric point
9,20894
Sequence
MKTYSEARARLRWYQGRYIDFDGWYGYQCADLAVDYIYWLLEIRMWGNAKDAINNDFKNMATVYENTPSFVPQIGDVAVFTKGIYKQYGHIGLVFNGGNTNQFLILEQNYDGNANTPAKLRWDNYYGCTHFIRPKYKSEGLMNKITNKVKPPAQKQSVNLQVK
Other Proteins in cluster: phalp2_27772
Total (incl. this protein): 52 Avg length: 234,4 Avg pI: 8,96
Protein ID Length (AA) pI
7kL3N 163 9,20894
1M1vw 130 7,76514
5BAgk 132 5,05511
78p7A 206 8,88486
7vBUN 188 9,59730
7vBUS 184 9,35889
7vBVR 163 9,04184
7vypd 143 7,85169
7wA74 170 9,05273
7wA8o 163 7,85600
E0Y3N1 251 9,25200
A0A223LH90 251 8,77281
A0A075LZV3 257 9,25200
A0A6M9Z395 251 8,77281
Q4ZCZ2 251 9,25200
A0A499SSS7 251 9,23131
A0A0H3U325 251 9,25200
A0A1J0MF80 251 8,77281
A0A1J0MF88 251 8,77281
A0A1J0MG26 251 8,77281
A0A1P8L6B2 251 9,25200
A0A1W6JPQ5 251 9,25200
A0A1X9H021 251 9,25200
A0A1X9H092 251 9,25200
A0A223LFP9 251 8,77281
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13870
7vCZb
 24 39,2% 140 2.478E-44
2 phalp2_796
28Kwv
 80 49,3% 160 1.354E-41
3 phalp2_368
7aJP9
 3 40,8% 142 1.528E-39
4 phalp2_25333
7ocj2
 56 37,5% 149 4.143E-30
5 phalp2_39580
6iLgH
 177 37,0% 151 3.764E-26
6 phalp2_24452
4BMZo
 66 33,0% 133 2.463E-22
7 phalp2_3543
4zM0o
 163 27,3% 139 2.953E-18
8 phalp2_30026
2tAM9
 32 30,2% 139 1.031E-17
9 phalp2_568
Omza
 65 31,8% 138 1.925E-17
10 phalp2_17703
71dZW
 23 32,0% 125 1.925E-17

Domains

Domains [InterPro]
CHAP
Disordered region
Representative sequence (used for alignment): 7kL3N (163 AA)
Member sequence: A0A1W6JQ85 (251 AA)
1 163 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage IME1346_01
[NCBI] 		1965492 Peeveelvirus > Peeveelvirus pv13
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KY653125 [NCBI]
CDS location
range 37488 -> 38243
strand +
CDS
ATGAAAACATACAGTGAAGCAAGAGCAAGGTTACGTTGGTATCAAGGTAGATATATTGATTTTGACGGTTGGTATGGTTACCAATGTGCAGATTTAGCAGTTGATTACATTTATTGGTTGTTAGAAATTAGAATGTGGGGAAATGCAAAAGATGCAATCAATAACGATTTTAAAAACATGGCAACAGTATATGAAAACACACCATCGTTTGTTCCACAAATAGGTGATGTGGCTGTATTTACCAAAGGAATATATAAACAATACGGTCATATTGGTTTAGTGTTTAATGGTGGTAATACAAACCAATTTTTAATTTTGGAACAGAACTATGACGGTAACGCAAATACGCCTGCAAAGTTACGTTGGGATAATTATTACGGCTGTACTCACTTTATTAGACCTAAGTATAAAAGTGAGGGCTTAATGAATAAGATCACAAATAAAGTTAAACCACCTGCTCAAAAAGCAGTCGGTAAATCTGCAAGTAAAATAACAGTTGGAAGTAAAGCGCCTTATAACCTTAAATGGTCAAAAGGTGCTTATTTTAATGCGAAAATCGACGGCTTAGGTGCTACTTCAGCCACTAGATACGGTGATAATCGTACTAACTATAGATTCGATGTTGGACAGGCTGTATACGCGCCTGGAACATTAATATATGTGTTTGAAATTATAGATGGTTGGTGTCGCATTTATTGGAACAATCATAATGAGTGGATATGGCATGAGAGATTGATTGTGAAAGAAGTGTTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A0H3U325
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A1P8L6B2
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A1W6JPQ5
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A1W6JQ85
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0A1X9H021
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50

Showing first 5 of 25 structures.

The structures below correspond to the cluster representative (7kL3N) rather than this protein.
PDB ID
7kL3N
Method AlphaFoldv2
Resolution 89.75
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50